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KMID : 0360220110520121541
Journal of the Korean Ophthalmological Society
2011 Volume.52 No. 12 p.1541 ~ p.1544
A Case of Cataract after Long-Term Use of Clonazepam in a Young Patient
Choo Byung-Ju

Kim Tai-Jin
Park Jung-Hyun
Kang Yong-Suk
Abstract
Purpose: To report a case of cataract after long-term use of clonazepam in a young patient, with a similar appearance to cataract induced by other psychotropic agents.

Case summary: A 37-year-old woman complained of a visual disturbance in both eyes. The best-corrected visual acuity was 0.8 in the right eye and 0.6 in the left eye. Bilateral cortical cataract was observed on slit-lamp examination, and no other ophthalmic abnormalities were found. Potential risk factors for cataract were investigated, including past medical and family history, revealing a 20-year history of oral clonazepam (0.5-1 mg/day), for the neurological diagnosis of ¡°chorea of unknown etiology¡±. Detailed medication history did not reveal long-term use of any other drugs which could have induced the cataract.

Conclusions: Because clonazepam use may induce cortical cataract, regular ophthalmologic examinations are necessary during long-term oral psychotropic therapy.
KEYWORD
Benzodiazepine, Cataract, Clonazepam
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